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HA5 Collagen Upgrade

HA5 Collagen Upgrade

Regular price $325.00 USD
Regular price Sale price $325.00 USD
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An Evolution in Hydration – Introducing the next-gen HA⁵®, now with 2X more hyaluronic acid. Enhanced with Hydra Collagen for instant hydration and smoothness, plus Advanced VITISENSCE® Technology to replenish natural humectants, including HA and help restore skin's hydration reservoir.

Provides immediate hydration lasting up to 48 hours. Enjoy visibly plump, dewy, and healthier-looking skin with fewer lines.

Silicone-free • Non-comedogenic • Sulfate-free • Lightweight • Fragrance-free • Paraben-free • Pilling-free

Key Ingredients

Advanced VITISENSCE® Technology

Features a blend of nutrients found in nature, targeting existing collagens within the skin to boost hydration naturally.

  • Avocado Oil Esters - Supports skin's natural hydration and skin's water-holding abilities
  • Vitamin F - Supports skin barrier and prevents water loss
  • Passion Fruit Seed Oil - Enhances skin health and supports skin's water and nutrition flow
  • Vitis Flower Stem Extract and Lotus Sprout Extract - Protect against oxidative stress

Proprietary HA⁵® Hydra Collagen Complex

Hydration Collagen - vegan collagen that attracts and retains water for instant hydration and smoothness

5 Forms of HA:

  • Vectorized Time Release HA - A SkinMedica® proprietary ingredient for sustained release of HA
  • Cross-linked HA - Provides long-lasting hydration
  • Encapsulated HA - For immediate hydration
  • Noncross-linked HA - For smoothness and hydration 
  • Nano-hyaluronic acid - Soothes skin

Service Disclaimer

Most SkinMedica® products are intended to meet the FDA's definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These SkinMedica® products are not intended to be drug products that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA and the statements have not been evaluated by the FDA.

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  • Lasting hydration

    Attracts and retains water for instant hydration and visibly plump, smooth skin

  • anti-aging

    In a clinical study, patients reported they looked ~ 3 years younger by week 12

  • strengthen skin barrier

    Clinically proven to improve hydration and support skin health by addressing the skin barrier and water-holding capacity

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our results speak for themselves

color photo Before
black and white After

Female, White, Age 59, Fitzpatrick Skin Type II. Non-retouched photos, taken in parallel polarized lighting of subject at baseline and after 12 weeks of using HA⁵® Hydra Collagen Replenish + Restore Hydrator.
Individual results may vary.

Frequently asked questions

FAQ

What differentiates HA⁵® Hydra Collagen Replenish + Restore Hydrator from the legacy HA⁵® Rejuvenating Hydrator product?

Modernizing our legacy HA⁵® formulation takes HA⁵® Hydra Collagen Replenish + Restore Hydrator to the next level of hydrator innovation. NEW Hydra Collagen is a vegan collagen that attracts and retains water for instant hydration and smoothness. ADVANCED VITISENSCE® TECHNOLOGY replenishes the natural HA, biohumectants, and hydration-boosting collagens within the skin to support the skin's hydration reservoir. Now, hydration lasts twice as long (48 hours vs 24 hours) compared to the original formulation.

What’s the difference between a moisturizer and a hydrator?

A moisturizer is a cosmetic cream or lotion made with humectants or occlusive or a combination of that prevents skin dryness. A hydrator is a cosmetic treatment product that promotes epidermal health by supporting the skin’s natural biomolecules, including HA, other humectants and hydration-boosting collagens.

What’s the difference between dehydrated and dry skin?

Dry skin is a skin type, while dehydration is a skin condition. In both, the skin undergoes trans-epidermal water loss, or evaporation of water from inside the body. With this water loss, the enzymes that normally help the skin shed cells cannot function properly, resulting in a buildup of cells that makes the skin look rough and dry, contributing to the appearance of fine lines and wrinkles. Dry skin can be genetic or a symptom of systemic disease. It is caused either by the inadequate production of oil, called sebum, or by an imbalance of fatty acids, ceramide, and cholesterol in the stratum corneum, the barrier layer of the skin. Age is also a factor since we experience a decline in a main hormone that triggers sebum production. Dehydrated skin still produces sebum, but is temporarily dry because of various factors, including environmental effects such as a dry climate, harsh detergents, or skin products. It is also caused by a temporary imbalance of fatty acids and ceramides in the skin’s barrier layer, resulting in a temporary spike in trans-epidermal water loss.